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U-0521

Chemical Structure : U-0521

CAS No.: 5466-89-7

U-0521 (U 0521, U0521)

Catalog No.: PC-27913Not For Human Use, Lab Use Only.

U-0521 is a potent and selective catechol O-methyltransferase (COMT) inhibitor with IC50 of 6 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

U-0521 is a potent and selective catechol O-methyltransferase (COMT) inhibitor with IC50 of 6 uM.

Physicochemical Properties

M.Wt 180.20
Formula C10H12O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(3,4-Dihydroxyphenyl)-2-methylpropan-1-one

References

1. Bäckström R, et al. J Med Chem. 1989 Apr;32(4):841-6.

2. Wilson VG, et al. Naunyn Schmiedebergs Arch Pharmacol. 1988 Apr;337(4):397-405.

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