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UBASHIN-2

Chemical Structure : UBASHIN-2

CAS No.:

UBASHIN-2 (UBASH3B-INhibitor)

Catalog No.: PC-28294Not For Human Use, Lab Use Only.

UBASHIN-2 is a small-molecule inhibitor targeting UBASH3B 2HP domain, disrupts mitotic localization of UBASH3B and Aurora B, inducing arrest and cell death during mitosis.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

UBASHIN-2 is a small-molecule inhibitor targeting UBASH3B 2HP domain, disrupts mitotic localization of UBASH3B and Aurora B, inducing arrest and cell death during mitosis.

Physicochemical Properties

M.Wt 568.08
Formula C28H34ClN7O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-2-((R)-2-(2-(4-chlorophenyl)acetamido)-3-phenylpropanamido)-5-guanidino-N-(2-oxo-2-(prop-2-yn-1-ylamino)ethyl)pentanamide

References

1. Pangou E, et al. EMBO Mol Med. 2026 Sep 22. doi: 10.1038/s44321-026-00519-0.

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