You are here:Home-Chemical Inhibitors & Agonists-Apoptosis-TNF-alpha-UCB-5307
UCB-5307

Chemical Structure : UCB-5307

CAS No.: 1515887-44-1

UCB-5307 (UCB5307)

Catalog No.: PC-49445Not For Human Use, Lab Use Only.

UCB-5307 is a small molecule compound inhibiting TNFR1 signalling and downstream function in vitro, bind directly to TNF with slow binding kinetics (KD= 6 nM).

Packing Price Stock Quantity
100 mg Get quote
250 mg Get quote
500 mg Get quote
1 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

UCB-5307 is a small molecule compound inhibiting TNFR1 signalling and downstream function in vitro, bind directly to TNF with slow binding kinetics (KD= 6 nM).

Physicochemical Properties

M.Wt 343.42
Formula C22H21N3O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-[(2,5-Dimethylphenyl)methyl]-α-4-pyridinyl-1H-benzimidazole-2-methanol

References

1. James O'Connell, et al. Nat Commun. 2019 Dec 19;10(1):5795.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: