Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : UHRF1 inhibitor UM63
CAS No.: 117-77-1
Catalog No.: PC-72248Not For Human Use, Lab Use Only.
UHRF1 inhibitor UM63 (UM63) is an anthraquinone compound that binds to the 5-methylcytosine (5mC) binding pocket of the SRA domain of UHRF1, inhibits the base-flipping process, which is crucial in the replication of DNA methylation profiles.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $188 | In stock | |
| 100 mg | $388 | In stock | |
| 500 mg | $688 | In stock | |
| 1 g | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
UHRF1 inhibitor UM63 (UM63) is an anthraquinone compound that binds to the 5-methylcytosine (5mC) binding pocket of the SRA domain of UHRF1, inhibits the base-flipping process, which is crucial in the replication of DNA methylation profiles; UM63 impaired the UHRF1/DNMT1 interaction and decreased the overall methylation of DNA in treated cells.
| M.Wt | 239.23 | |
| Formula | C14H9NO3 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
|
|
| Chemical Name/SMILES |
|
|
1. Liliyana Zaayter, et al. Chemistry. 2019 Oct 17;25(58):13363-13375.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
