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Chemical Structure : UKH-1114
Catalog No.: PC-61104Not For Human Use, Lab Use Only.
UKH-1114 (UKH1114) is a potent, sigma 2 receptor/Tmem97 agonist with Ki of 46 nM.
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UKH-1114 (UKH1114) is a potent, selective sigma 2 receptor/Tmem97 agonist with Ki of 46 nM.
UKH-1114 displays high selectivity for σ2R/Tmem97 versus >50 other proteins, including 5-HT receptors.
UKH-1114 relieves spared nerve injury-induced mechanical hypersensitivity without producing any motor impairment.
| M.Wt | 75.435 | |
| Formula | C22H24F3NO | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Sahn JJ, et al. ACS Chem Neurosci. 2017 Aug 16;8(8):1801-1811.
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