Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : ULK-100
Catalog No.: PC-35708Not For Human Use, Lab Use Only.
ULK-100 (ULK100) is a potent and selective ULK1 inhibitor with in vitro IC50 of 1.6 nM, inhibits ULK2 with IC50 of 2.6 nM.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
ULK-100 (ULK100) is a potent and selective ULK1 inhibitor with in vitro IC50 of 1.6 nM, inhibits ULK2 with IC50 of 2.6 nM。
ULK-100 reduces Ser15 phosphorylation in a concentration-dependent manner in cell-based assay (EC50=83 nM), which is more potent than SBI-0206965 showing a cellular EC50 of 2.4 uM。
ULK-100 displays desirable kinome selectivity profile.
| M.Wt | 571.66 | |
| Formula | C29H32F3N5O2S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Martin KR, et al. iScience. 2018 Oct 26;8:74-84. doi: 10.1016/j.isci.2018.09.012.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
