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USP5-Cav3.2 inhibitor II-1

Chemical Structure : USP5-Cav3.2 inhibitor II-1

CAS No.:

USP5-Cav3.2 inhibitor II-1

Catalog No.: PC-72884Not For Human Use, Lab Use Only.

USP5-Cav3.2 inhibitor II-1 is a small molecule inhibitor of USP5-Cav3.2 interaction, without affecting the enzymatic activity of USP5.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

USP5-Cav3.2 inhibitor II-1 is a small molecule inhibitor of USP5-Cav3.2 interaction, without affecting the enzymatic activity of USP5.
II-1 inhibited both phases of formalin-induced nocifensive behaviors in mice.
Cav3.2 is required for the action of II-1.
II-1 also mediated a robust inhibition of mechanical allodynia induced by injury to the sciatic nerve.

Physicochemical Properties

M.Wt 263.326
Formula C9H13NO4S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Month
Shipping
Solubility

Chemical Name/SMILES

References

1. Garcia-Caballero A, et al. ACS Chem Neurosci. 2022 Feb 16;13(4):524-536.

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