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Umifenovir

Chemical Structure : Umifenovir

CAS No.: 131707-25-0

Umifenovir (Arbidol)

Catalog No.: PC-49477Not For Human Use, Lab Use Only.

Umifenovir (Arbidol) is a broad-spectrum antiviral compound that blocks viral fusion, demonstrates activity against a number of enveloped and non-enveloped viruses, including influenza A and B viruses, HCV and SARS-CoV-2.

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Biological Activity

Umifenovir (Arbidol) is a broad-spectrum antiviral compound that blocks viral fusion, demonstrates activity against a number of enveloped and non-enveloped viruses, including influenza A and B viruses, HCV and SARS-CoV-2.
Umifenovir inhibits membrane fusion of influenza virus. specific antiviral action against both influenza A and influenza B viruses.
Umifenovir exhibits modulatory effects on the immune system, stimulates a humoral immune response, induces interferon-production, and stimulates the phagocytic function of macrophages.

Physicochemical Properties

M.Wt 477.42
Formula C22H25BrN2O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

ethyl 6-bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylthio)methyl)-1H-indole-3-carboxylate

References

1. Boriskin YS, et al. Curr Med Chem. 2008;15(10):997-1005.

2. Boriskin YS, et al. Virol J. 2006 Jul 19;3:56.

3. Vankadari N. Int J Antimicrob Agents. 2020 Aug;56(2):105998.

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