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Chemical Structure : VCP979
Catalog No.: PC-49694Not For Human Use, Lab Use Only.
VCP979 (VCP-979) is a novel selective small molecule p38 MAPK inhibitor with a significantly greater affinity for the active form of p38 MAPK, has significant anti-fibrotic effects in vitro and in vivo.
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VCP979 (VCP-979) is a novel selective small molecule p38 MAPK inhibitor with a significantly greater affinity for the active form of p38 MAPK, has significant anti-fibrotic effects in vitro and in vivo.
VCP979 significantly promoted axonal/white matter (WM) remodeling, neural progenitor cell migration, and improved functional recovery in T2DM mice.
VCP979 improved axonal/WM remodeling and functional outcomes in a diabetic mouse stroke mode.
VCP979 effectively suppressed orthotopic pancreatic cancer growth and metastasis.
VCP979 effectively reduced renal fibrosis, extracellular matrix accumulation, and alleviated epithelial-mesenchymal transition in UUO rats.
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| Appearance | Solid | |
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| Solubility |
10 mM in DMSO |
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