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Chemical Structure : VDR 4-1
Catalog No.: PC-61773Not For Human Use, Lab Use Only.
VDR 4-1 is a novel non-steroidal, small-molecule agonist of vitamin D receptor (VDR).
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VDR 4-1 is a novel non-steroidal, small-molecule agonist of vitamin D receptor (VDR); demonstrates potent transcriptional activities in a VDR reporter gene assay, and significantly ameliorates cardiac hypertrophy in cell culture and in animal models; also effectively suppresses secondary hyperparathyroidism in 1α-hydroxylase knockout mice; does not induce hypercalcemia at high doses in contrast to naturally occurring VDR agonist (1,25-D3 or calcitriol).
| M.Wt | 512.061 | |
| Formula | C28H30ClNO4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Khedkar SA, et al. Sci Rep. 2017 Aug 16;7(1):8427.
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