Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : VPC-70619
Catalog No.: PC-72931Not For Human Use, Lab Use Only.
VPC-70619 (VPC70619) is a selective small-molecule inhibitor of N-Myc transcription in NMYC transcription inhibition assays.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
VPC-70619 (VPC70619) is a selective small-molecule inhibitor of N-Myc transcription in NMYC transcription inhibition assays.
VPC-70619 blocks DNA binding to N-Myc-Max without disrupting the heterodimer.
VPC-70619 inhibits N-Myc-dependant cellular growth showing potential selective activity against N-Myc expressing cells.
At 10 uM, VPC-70619 had an inhibition of 99.4% in IMR32 cells while having a minimal effect of 14% in HO15.19 cells.
| M.Wt | 364.712 | |
| Formula | C16H8ClF3N4O | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Anh-Tien Ton, et al. Int J Mol Sci. 2022 Feb 26;23(5):2588.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
