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VPS34 inhibitor 5

Chemical Structure : VPS34 inhibitor 5

CAS No.: 2770104-92-0

VPS34 inhibitor 5

Catalog No.: PC-20375Not For Human Use, Lab Use Only.

VPS34 inhibitor 5 is a potent, selective, and orally bioavailable VPS34 inhibitor with IC50 of 83 nM, >95-fold selectivity over other PIK family kinases.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

VPS34 inhibitor 5 is a potent, selective, and orally bioavailable VPS34 inhibitor with IC50 of 83 nM, >95-fold selectivity over other PIK family kinases.

Physicochemical Properties

M.Wt 276.34
Formula C14H20N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(5aS,8aR)-2-((R)-3-methylmorpholino)-5,5a,6,7,8,8a-hexahydro-4H-cyclopenta[e]pyrazolo[1,5-a]pyrazin-4-one

References

1. Dennis X Hu, et al. J Med Chem. 2022 Sep 8;65(17):11500-11512.

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