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Chemical Structure : VT-105
CAS No.: 2417718-38-6
Catalog No.: PC-49540Not For Human Use, Lab Use Only.
VT-105 (VT105) is a highly potent and selective TEAD inhibitor, selectively inhibit YAP/TAZ-TEAD promoted gene transcription with IC50 of 10.4 nM in YAP reporter assays, blocks TEAD auto-palmitoylation, and disrupts interaction between YAP/TAZ and TEAD.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $298 | In stock | |
| 10 mg | $458 | In stock | |
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| 50 mg | Get quote | ||
| 100 mg | Get quote |
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VT-105 (VT105) is a highly potent and selective TEAD inhibitor, selectively inhibits YAP/TAZ-TEAD promoted gene transcription with IC50 of 10.4 nM in YAP reporter assays.
VT-105 blocks TEAD auto-palmitoylation, and disrupts interaction between YAP/TAZ and TEAD.
| M.Wt | 421.42 | |
| Formula | C24H18F3N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-[(1S)-1-(2-Pyridinyl)ethyl]-8-[4-(trifluoromethyl)phenyl]-3-quinolinecarboxamide |
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1. Tracy T Tang, et al. Mol Cancer Ther. 2021 Jun;20(6):986-998.
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