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VTD227

Chemical Structure : VTD227

CAS No.: 330858-64-5

VTD227

Catalog No.: PC-47033Not For Human Use, Lab Use Only.

VTD227 is a small molecule Vpr-targeting HIV-1 inhibitor, directly binds to Vpr with Kd of 8.8 uM, inhibits HIV-1 replication in monocyte-derived macrophages (MDM) with IC50 of 0.78 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

VTD227 is a small molecule Vpr-targeting HIV-1 inhibitor, directly binds to Vpr with Kd of 8.8 uM, inhibits HIV-1 replication in monocyte-derived macrophages (MDM) with IC50 of 0.78 uM.

Physicochemical Properties

M.Wt 329.356
Formula C17H19N3O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

References

1. Hirotaka Sato, et al. Viruses. 2022 Jun 16;14(6):1321.

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