VU0364572 TFA

Chemical Structure : VU0364572 TFA

CAS No.: 1240514-89-9

Catalog No.: PC-26730Not For Human Use, Lab Use Only.

VU0364572 TFA is a potent, selective, orally active, allosteric agonist of M1 muscarinic receptor with an EC50 of 0.11 uM, shows neuroprotective potential for preventing memory impairments and reducing neuropathology in Alzheimer's disease.

Packing	Price	Stock
5 mg	$158	In stock
10 mg	$248	In stock
25 mg	$428	In stock
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Biological Activity

Physicochemical Properties

M.Wt	487.52
Formula	C23H32F3N3O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Ethyl (R)-3-(2-methylbenzamido)-[1,4'-bipiperidine]-1'-carboxylate 2,2,2-trifluoroacetate

References

1. Lebois EP, et al. ACS Chem Neurosci. 2017 Jun 21;8(6):1177-1187.

2. Lebois EP, et al. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6451-5.

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VU0364572 TFA

Biological Activity

Physicochemical Properties

References

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