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VU0364739

Chemical Structure : VU0364739

CAS No.: 1244639-78-8

VU0364739 (VU 0364739)

Catalog No.: PC-49071Not For Human Use, Lab Use Only.

VU0364739 is a potent, selective allosteric inhibitor of phospholipase D2 (PLD2) with cellular IC50 of 20 nM, >75-fold selectivity over PLD1.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

VU0364739 is a potent, selective allosteric inhibitor of phospholipase D2 (PLD2) with cellular IC50 of 20 nM, >75-fold selectivity over PLD1.

Physicochemical Properties

M.Wt 446.526
Formula C26H27FN4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-[2-[1-(3-Fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]ethyl]-2-naphthalenecarboxamide

References

1. Sarah A. Scott, et al. Bethesda (MD): National Center for Biotechnology Information (US); 2010–.2012 Apr 5 [updated 2013 Mar 14].

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