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Chemical Structure : VU533
Catalog No.: PC-20922Not For Human Use, Lab Use Only.
VU533 is a small molecule activator of N-acyl-phosphatidylethanolamine hydrolyzing phospholipase D (NAPE-PLD) with EC50 of 0.3 uM, enhances efferocytosis by macrophages.
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VU533 is a small molecule activator of N-acyl-phosphatidylethanolamine hydrolyzing phospholipase D (NAPE-PLD) with EC50 of 0.3 uM, enhances efferocytosis by macrophages.
VU533 (10 uM) increases the NAPE-PLD activity of RAW264.7 macrophages.
VU533 enhances efferocytosis in a NAPE-PLD-dependent manner in bone-marrow derived macrophages (BMDM).
| M.Wt | 447.54 | |
| Formula | C21H22FN3O3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Jonah E Zarrow, et al. bioRxiv. 2023 Feb 28;2023.01.25.525554.
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