VU6008677

Chemical Structure : VU6008677

Catalog No.: PC-24343Not For Human Use, Lab Use Only.

VU6008677 is a potent, selective M4 mAChR positive allosteric modulator (PAM) with EC50 of 163 nM (hM4), inactive against hM2.

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Biological Activity

VU6008677 is a potent, selective M4 mAChR positive allosteric modulator (PAM) with EC50 of 163 nM (hM4), inactive against hM2.

M.Wt	288.74
Formula	C14H13ClN4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	8-chloro-N-cyclopropyl-7,9-dimethylpyrido[3',2':4,5]furo[3,2-d]pyrimidin-4-amine

1. Capstick RA, et al. ACS Med Chem Lett. 2024 Jul 3;15(8):1358-1366.