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Chemical Structure : VUF15485
Catalog No.: PC-21785Not For Human Use, Lab Use Only.
VUF15485 is a small-molecule agonist of the atypical chemokine receptor ACKR3 with binding pIC50 of 8.3, and pEC50 of 7.6 in BRET-based β-arrestin2 recruitment assay.
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VUF15485 is a small-molecule agonist of the atypical chemokine receptor ACKR3 with binding pIC50 of 8.3, and pEC50 of 7.6 in BRET-based β-arrestin2 recruitment assay.
VUF15485 is highly selective for ACKR3 against a chemokine receptor panel (agonist and antagonist mode).
| M.Wt | 470.59 | |
| Formula | C27H35FN2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Aurelien Zarca, et al. Mol Pharmacol. 2024 Feb 12:MOLPHARM-AR-2023-000835.
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