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Chemical Structure : VX-984
CAS No.: 1562396-65-9
Catalog No.: PC-61971Not For Human Use, Lab Use Only.
VX-984 (M9831) is a potent, selective inhibitor of DNA-PK with IC50 of 88 nM for inhibition of DNA-PKcs autophosphorylation (Ser2056) in A549 lung cancer cells, with good selectivity versus other PI3K family members.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 2 mg | $358 | In stock | |
| 5 mg | $558 | In stock | |
| 10 mg | $958 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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VX-984 (M9831) is a potent, selective inhibitor of DNA-PK with IC50 of 88 nM for inhibition of DNA-PKcs autophosphorylation (Ser2056) in A549 lung cancer cells, with good selectivity versus other PI3K family members.
| M.Wt | 401.4702 | |
| Formula | C22H19D2N7O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
8-[(1S)-1-Methyl-2-[(2'-methyl[4,5'-bipyrimidin]-6-yl-4',6'-d2)amino]ethyl]-4-quinolinecarboxamide |
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1. Harnor SJ, et al. ChemMedChem. 2017 Jun 21;12(12):895-900.
2. D. Boucher, R, et al. AACR; Abstract No. 3716.
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