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Chemical Structure : Vipadenant
CAS No.: 442908-10-3
Catalog No.: PC-42717Not For Human Use, Lab Use Only.
Vipadenant (BIIB014) is a potent and selective A2A adenosine receptor antagonist with Ki of 1.3 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $298 | In stock | |
| 50 mg | $478 | In stock | |
| 100 mg | Get quote |
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Vipadenant (BIIB014) is a potent and selective A2A adenosine receptor antagonist with Ki of 1.3 nM.
Vipadenant (BIIB014) displays 50-fold selectivity over A1 and A2B, and no activity against A3, P450 isoforms and hERG.
Vipadenant (BIIB014) shows excellent preclinical pharmacokinetics, and demonstrates strong oral activity in commonly used models of Parkinson's disease.
| M.Wt | 321.3366 | |
| Formula | C16H15N7O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 31 mg/mL |
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| Chemical Name/SMILES |
3H-1,2,3-Triazolo[4,5-d]pyrimidin-5-amine, 3-[(4-amino-3-methylphenyl)methyl]-7-(2-furanyl)- |
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1. Gillespie RJ, et al. J Med Chem. 2009 Jan 8;52(1):33-47.
2. Pinna A. Expert Opin Investig Drugs. 2009 Nov;18(11):1619-31.
3. Brooks DJ, et al. Clin Neuropharmacol. 2010 Mar-Apr;33(2):55-60.
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