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Chemical Structure : Vorolanib
CAS No.: 1013920-15-4
Catalog No.: PC-61437Not For Human Use, Lab Use Only.
Vorolanib (CM-082) is an orally available, small molecule dual VEGFR/PDGFR kinase inhibitor with antiangiogenic and antineoplastic activities.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $198 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | $528 | In stock | |
| 100 mg | $898 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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Vorolanib (CM-082) is an orally available, small molecule dual VEGFR/PDGFR kinase inhibitor with antiangiogenic and antineoplastic activities.
Vorolanib (CM-082) inhibits tumor angiogenesis and tumor cell proliferation, and induces tumor cell death.
Vorolanib (CM-082) has been shown to reduce tissue toxicity by 95 percent compared with first-generation kinase inhibitors.
| M.Wt | 439.4914 | |
| Formula | C23H26FN5O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(S,Z)-N-(1-(dimethylcarbamoyl)pyrrolidin-3-yl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide |
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1. Jackson TL, et al. JAMA Ophthalmol. 2017 Jul 1;135(7):761-767.
2. Hussain RM, et al. Expert Opin Emerg Drugs. 2017 Sep;22(3):235-246.
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