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Vustanaciclib

Chemical Structure : Vustanaciclib

CAS No.: 2531743-46-9

Vustanaciclib (GDC-4198, RGT-419B)

Catalog No.: PC-26363Not For Human Use, Lab Use Only.

Vustanaciclib (GDC-4198, RGT-419B) is a potent CDK2/4/6 inhibitor.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Vustanaciclib (GDC-4198, RGT-419B) is a potent CDK2/4/6 inhibitor.

Physicochemical Properties

M.Wt 470.58
Formula C26H30N8O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
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Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Piperidinone, 4-(dimethylamino)-1-[6-[[4-[3-(1-methylethyl)pyrazolo[1,5-a]pyridin-5-yl]-2-pyrimidinyl]amino]-3-pyridinyl]-, (4S)-

References

1. Patent WO2020224568 A1.

2. Patent WO2021226140 A1

3. S. A. Wander, et al. Clin Cancer Res (2026) 32 (4_Supplement): PS1-11-07.

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