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Chemical Structure : W146
CAS No.: 909725-61-7
Catalog No.: PC-63010Not For Human Use, Lab Use Only.
W146 is a potent, selective S1P1 antagonist with Ki of 18 nM, displays no effect at S1P2, S1P3 or S1P5, enhances capillary leakage and restores lymphocyte egress in vivo. .
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|---|---|---|---|
| 2 mg | $458 | In stock | |
| 5 mg | $758 | In stock | |
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| 25 mg | Get quote | ||
| 100 mg | Get quote |
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W146 is a potent, selective S1P1 antagonist with Ki of 18 nM, displays no effect at S1P2, S1P3 or S1P5, enhances capillary leakage and restores lymphocyte egress in vivo.
| M.Wt | 342.376 | |
| Formula | C16H27N2O4P | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
[(3R)-3-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid |
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1. Sanna MG, et al. Nat Chem Biol. 2006 Aug;2(8):434-41.
2. Gonzalez-Cabrera PJ, et al. Mol Pharmacol. 2008 Nov;74(5):1308-18.
3. Tarrasón G, et al. Int Immunopharmacol. 2011 Nov;11(11):1773-9.
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