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Chemical Structure : WAY-362692
Catalog No.: PC-63016Not For Human Use, Lab Use Only.
WAY-362692 is a small molecule inhibitor of the secreted frizzled-related protein sFRP-1 with IC50 of 20 nM in FP binding assay.
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WAY-362692 is a small molecule inhibitor of the secreted frizzled-related protein sFRP-1 with IC50 of 20 nM in FP binding assay.
WAY-362692 exhibits Wnt signaling inhibition in U2-OS cell lines with EC50 of 30 nM.
WAY-362692 increases total bone area (75%) relative to the vehicle control in an ex vivo mouse calvaria model for bone formation.
| M.Wt | 644.725 | |
| Formula | C28H35F3N4O6S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Moore WJ, et al. J Med Chem. 2009 Jan 8;52(1):105-16.
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