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WEHI-601

Chemical Structure : WEHI-601

CAS No.: 2363124-71-2

WEHI-601 (Cbz-Cav(NH2)-CyHexGly-Sta-NH(CH2)2PH.TFA)

Catalog No.: PC-49832Not For Human Use, Lab Use Only.

WEHI-601 is a potent, small molecule inhibitor of the aspartic proteases Plasmepsin X (PMX) with IC50 of 5 nM, possess potent anti-parasitic activity (P. falciparum parasite, IC50=9 nM).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

WEHI-601 is a potent, small molecule inhibitor of the aspartic proteases Plasmepsin X (PMX) with IC50 of 5 nM, possess potent anti-parasitic activity (P. falciparum parasite, IC50=9 nM).

Physicochemical Properties

M.Wt 823.91
Formula C39H56F3N7O9
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

References

1. William Nguyen, et al. Eur J Med Chem. 2018 Jun 25;154:182-198.

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