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WIN 4-88

Chemical Structure : WIN 4-88

CAS No.:

WIN 4-88 (WIN4-88)

Catalog No.: PC-26689Not For Human Use, Lab Use Only.

WIN 4-88 is a potent small molecule inhibitor of Cryptosporidium parvum Calcium-dependent protein kinase 1 (CpCDPK1) with IC50 of 56 nM, exhibits growth inhibition of zoonotic C. parvum, anthroponotic C. parvum and C. hominis Tu502 with EC50 of 42, 30 and 62 nM respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

WIN 4-88 is a potent small molecule inhibitor of Cryptosporidium parvum Calcium-dependent protein kinase 1 (CpCDPK1) with IC50 of 56 nM, exhibits growth inhibition of zoonotic C. parvum, anthroponotic C. parvum and C. hominis Tu502 with EC50 of 42, 30 and 62 nM respectively.

Physicochemical Properties

M.Wt 560.02
Formula C25H26ClN5O6S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-((6-(2-chloro-4-methoxyphenyl)-8-(2,3-dihydroxypropyl)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)-N,N-dimethylbenzenesulfonamide

References

1. Wijitrmektong W, et al. J Infect Dis. 2026 May 4:jiag242.

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