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WNK inhibitor 7

Chemical Structure : WNK inhibitor 7

CAS No.: 2125724-72-1

WNK inhibitor 7 (WNK-IN-7)

Catalog No.: PC-61065Not For Human Use, Lab Use Only.

WNK inhibitor 7 (WNK-IN-7) is a potent, selectiive inhibitor of WNK1 kinase with IC50 of 95 nM, shows IC50 of 1.39 uM in the cellular OSR1 phosphorylation assay with reasonable aqueous solubility.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    WNK inhibitor 7 (WNK-IN-7) is a potent, selectiive inhibitor of WNK1 kinase with IC50 of 95 nM, shows IC50 of 1.39 uM in the cellular OSR1 phosphorylation assay with reasonable aqueous solubility.

    Physicochemical Properties

    M.Wt 399.538
    Formula C26H29N3O
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-((1-(2-(3-methoxyphenyl)-5-methylpyridin-4-yl)-1H-indol-3-yl)methyl)-2-methylpropan-1-amine

    References

    1. Yamada K, et al. ACS Chem Biol. 2016 Dec 16;11(12):3338-3346.

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