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Chemical Structure : WNN2048-F004
Catalog No.: PC-49668Not For Human Use, Lab Use Only.
WNN2048-F004 (Compound 4a) is a potent, covalent, nonpeptidomimetic SARS-CoV-2 main protease (Mpro) inhibitor with biochemical IC50 of 103 nM, covalently binds to the substrate-binding pocket (Cys145) of SARS-CoV-2 Mpro.
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WNN2048-F004 (Compound 4a) is a potent, covalent, nonpeptidomimetic SARS-CoV-2 main protease (Mpro) inhibitor with biochemical IC50 of 103 nM, covalently binds to the substrate-binding pocket (Cys145) of SARS-CoV-2 Mpro.
WNN2048-F004 showed good anti-SARS-CoV-2 infection activity in cell culture with IC50 value of 21.3 µmol/L without cytotoxicity effect.
| M.Wt | 274.12 | |
| Formula | C10H5Cl2NO2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Zang Y, et al. Protein Cell. 2022 Sep 28;14(1):17-27.
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