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WP-1034

Chemical Structure : WP-1034

CAS No.: 857064-42-7

WP-1034 (WP1034)

Catalog No.: PC-26209Not For Human Use, Lab Use Only.

WP-1034 is a small molecule JAK-STAT inhibitor, blocks Stat3 and Stat5 and induces caspase-dependent apoptosis in acute myeloid leukemia (AML).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

WP-1034 is a small molecule JAK-STAT inhibitor, blocks Stat3 and Stat5 and induces caspase-dependent apoptosis in acute myeloid leukemia (AML).

Physicochemical Properties

M.Wt 321.34
Formula C18H15N3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R,E)-2-cyano-3-(4-nitrophenyl)-N-(1-phenylethyl)acrylamide

References

1. Stefan Faderl, et al. Anticancer Res. 2005 May-Jun;25(3B):1841-50.

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