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Chemical Structure : WX-UK1
CAS No.: 220355-63-5
Catalog No.: PC-42144Not For Human Use, Lab Use Only.
WX-UK1 (UKI-1) is a small synthetic serine protease uPA (urokinase-type plasminogen activator) inhibitor that blocks tumor cell invasion, metastasis and primary tumor growth.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $280 | In stock | |
| 10 mg | $400 | In stock | |
| 50 mg | $1200 | In stock | |
| 100 mg | $1680 | In stock | |
| 250 mg | Get quote | ||
| 1 g | Get quote |
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WX-UK1 (UKI-1) is a small synthetic serine protease uPA (urokinase-type plasminogen activator) inhibitor that blocks tumor cell invasion, metastasis and primary tumor growth.
WX-UK1 selectively inhibits tumour-related proteases from rats and humans such as uPA, plasmin, or thrombin in the sub or low micromolar range.
WX-UK1 impaired primary tumour growth and metastasis of BN472 rat breast cancer.
| M.Wt | 613.8111 | |
| Formula | C32H47N5O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 28 mg/mL |
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| Chemical Name/SMILES |
1-Piperazinecarboxylic acid, 4-[(2S)-3-[3-(aminoiminomethyl)phenyl]-1-oxo-2-[[[2,4,6-tris(1-methylethyl)phenyl]sulfonyl]amino]propyl]-, ethyl ester |
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1. Ertongur S, et al. Int J Cancer. 2004 Jul 20;110(6):815-24.
2. Schuh T, et al. Biol Chem. 2003 Feb;384(2):311-5.
3. Setyono-Han B, et al. Thromb Haemost. 2005 Apr;93(4):779-86.
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