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Chemical Structure : Windorphen
CAS No.: 19881-70-0
Catalog No.: PC-70121Not For Human Use, Lab Use Only.
Windorphen is a potent, selective inhibitor of p300 histone acetyltransferase (IC50=4.2 uM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $158 | In stock | |
| 25 mg | $258 | In stock | |
| 50 mg | $398 | In stock | |
| 100 mg | Get quote |
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Windorphen is a potent, selective inhibitor of p300 histone acetyltransferase (IC50=4.2 uM).
Windorphen displays >10-fold selectivity over other histone acetyltransferases.
Windorphen inhibits Wnt3a-inducible TOPFLASH-luciferase activity with IC50 of 1.5 uM, exhibits remarkable specificity toward β-catenin-1 function and selectively blocks the Wnt signal required for ventral development.
Windorphen robustly and selectively kills cancer cells that harbor Wnt-activating mutations.
| M.Wt | 302.75 | |
| Formula | C17H15ClO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(Z)-3-chloro-2,3-bis(4-methoxyphenyl)acrylaldehyde |
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1. Hao J, et al. Cell Rep. 2013 Sep 12;4(5):898-904.
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