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Chemical Structure : XCT0135908
CAS No.: 300837-31-4
Catalog No.: PC-20774Not For Human Use, Lab Use Only.
XCT0135908 (BRF001) is a highly selective activator of Nurr1-RXR heterodimers, stimulates dopamine (DA) neuron survival.
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| 25 mg | $798 | In stock | |
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XCT0135908 (BRF001) is a highly selective activator of Nurr1-RXR heterodimers, stimulates dopamine (DA) neuron survival.
XCT0135908 (1 uM) is highly selective in activation of heterodimers formed between Gal4-Nurr1 and cotransfected RXR in African green monkey CV-1 cells.|
XCT0135908 is strictly selective for RXR/Nurr1 heterodimers at 1 uM.
The RXR antagonist LG1208 completely abolished activation by XCT0135908.
| M.Wt | 345.40 | |
| Formula | C21H19N3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
O=C(O)C1=CC=C(NC2=NC(C3=CC=CC=C3)=NC(C)=C2CC=C)C=C1 |
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1. Wallen-Mackenzie A, et al. Genes Dev. 2003 Dec 15;17(24):3036-47.
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