YCH3292 | PARP inhibitor | Probechem Biochemicals

Chemical Structure : YCH3292

YCH3292 (YCH-3292)

Catalog No.: PC-27880Not For Human Use, Lab Use Only.

YCH3292 is a potent, new-generation antiresistant PARP inhibitor with IC50 of <0.001 nM for PARP1/2, exhibits robust antiproliferative activity against Capan-1/TP cells with IC50 of 0.23 nM, overcomes acquired resistance to PARPi.

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Biological Activity

Physicochemical Properties

M.Wt	510.52
Formula	C28H23FN6O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1(2H)-Phthalazinone, 4-[[3-[[3-(5-cyclopropyl-2-furanyl)-5,6-dihydro-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]carbonyl]-4-fluorophenyl]methyl]-

References

1. Sun Y, et al. Eur J Med Chem. 2026 Feb 15;304:118507.

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YCH3292 (YCH-3292)

Biological Activity

Physicochemical Properties

References

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