Chemical Structure : YM-1
CAS No.:
409086-68-6
YM-1
(YM1, Hsp70 inhibitor)
Catalog No. : PC-62198Not For Human Use, Lab Use Only.
YM-1 is a close derivative of MTK-077 that allosterically promotes Hsp70 binding to unfolded substrates, specificly binds to Hsp70 with Kd of 4.9 uM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6219801
Biological Activity
YM-1 is a close derivative of MTK-077 that allosterically promotes Hsp70 binding to unfolded substrates, specificly binds to Hsp70 with Kd of 4.9 uM.
Physicochemical Properties
M.Wt
417.97
Formula
C20H20ClN3OS2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-((Z)-((E)-3-Ethyl-5-(3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-oxothiazolidin-2-ylidene)methyl)-1-methylpyridin-1-ium chloride
References
1. Wang AM, et al. Nat Chem Biol
2. Morishima Y, et al. Biochemistry
3. Colvin TA, et al. Cancer Res
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