Catalog No.: PC-25195Not For Human Use, Lab Use Only.
YM-244769 is a potent, selective and orally active Na+/Ca2+ exchanger (NCX) inhibitor, inhibits initial rates of 45Ca2+ uptake into NCX1, NCX2, and NCX3 transfectants with IC50 of 68 nM, 96 nM and 18 nM respectively.
YM-244769 is a potent, selective and orally active Na+/Ca2+ exchanger (NCX) inhibitor, inhibits initial rates of 45Ca2+ uptake into NCX1, NCX2, and NCX3 transfectants with IC50 of 68 nM, 96 nM and 18 nM respectively. YM-244769 is not only experimentally useful as a NCX inhibitor that preferentially inhibits NCX3, but also has therapeutic potential as a new neuroprotective drug.
