YT-III-31

Chemical Structure : YT-III-31

Catalog No.: PC-28048Not For Human Use, Lab Use Only.

YT-III-31 is a selective positive allosteric modulator (PAM) of α3βγ2 GABAA receptor (GABAAR) with EC50 of 153 nM, Emax=917%.

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Biological Activity

YT-III-31 is a selective positive allosteric modulator (PAM) of α3βγ2 GABAA receptor (GABAAR) with EC50 of 153 nM, Emax=917%.

M.Wt	340.39
Formula	C21H16N4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	8-ethynyl-N-methyl-6-phenyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxamide

1. Batinić B, et al. Eur Neuropsychopharmacol. 2018 Aug;28(8):903-914.

2. Berro LF, et al. Alcohol Clin Exp Res. 2019 May;43(5):791-802.