YU-101 |CAS:254888-42-1 Probechem Biochemicals

Chemical Structure : YU-101

Catalog No.: PC-60971Not For Human Use, Lab Use Only.

A potent, specific proteasome β5 subunit inhibitor with IC50 of 0.26 uM, 7.3 and 17.3-fold selectivity over β2i and β1i subunit, respecitvely..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A potent, specific proteasome β5 subunit inhibitor with IC50 of 0.26 uM, 7.3 and 17.3-fold selectivity over β2i and β1i subunit, respecitvely.

M.Wt	634.818
Formula	C36H50N4O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-((S)-2-acetamido-4-phenylbutanamido)-4-methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pentanamide

1. Screen M, et al. J Biol Chem. 2010 Dec 17;285(51):40125-34.