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Chemical Structure : YX-A-1
Catalog No.: PC-38108Not For Human Use, Lab Use Only.
YX-A-1 is a small-molecule modulator of human islet amyloid polypeptide (hIAPP) assembly, specifically enhances amyloid formation.
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YX-A-1 is a small-molecule modulator of human islet amyloid polypeptide (hIAPP) assembly, specifically enhances amyloid formation.
YX-A-1 accelerates wt hIAPP assembly, even when added in substoichiometric concentration ratios (e.g. at a peptide:YX-A-1 molar ratio of 1:0.5 the t50 is reduced ~1.5-fold).
YX-A-1 is a useful chemical tools to study hIAPP aggregation.
| M.Wt | 446.526 | |
| Formula | C26H27FN4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yong Xu, et al. Nat Commun. 2022 Feb 24;13(1):1040.
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