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Chemical Structure : Yoda1
CAS No.: 448947-81-7
Catalog No.: PC-45542Not For Human Use, Lab Use Only.
Yoda1 is a potent, selective Piezo1 ion channel activator, affects the sensitivity and the inactivation kinetics of mechanically induced responses in cells.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $198 | In stock | |
| 100 mg | $458 | In stock | |
| 500 mg | Get quote |
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Yoda1 is a potent, selective Piezo1 ion channel activator, affects the sensitivity and the inactivation kinetics of mechanically induced responses in cells.
Yoda1 activates purified Piezo1 channels in the absence of other cellular components.
Yoda1 potentiates shear-dependent platelet Ca2+ transients.
| M.Wt | 355.2654 | |
| Formula | C13H8Cl2N4S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 34 mg/mL |
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| Chemical Name/SMILES |
Pyrazine, 2-[5-[[(2,6-dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]- |
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1. Syeda R, et al. Elife. 2015 May 22;4.
2. Ilkan Z, et al. J Biol Chem. 2017 Apr 17. pii: jbc.M116.766196.
3. Wang S, et al. J Clin Invest. 2016 Dec 1;126(12):4527-4536.
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