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Chemical Structure : Z-505 hydrochloride
Catalog No.: PC-62603Not For Human Use, Lab Use Only.
Z-505 hydrochloride is a novel, orally active ghrelin (GHSR1a) agonist with EC50 of 2.08 nM and 5.46 nM for rat and mouse GHSR1a, respectively.
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Z-505 hydrochloride is a novel, orally active ghrelin (GHSR1a) agonist with EC50 of 2.08 nM and 5.46 nM for rat and mouse GHSR1a, respectively;attenuates the progression of cancer cachexia via anabolic hormones in vivo, significantly improves the cisplatin-induced reduction in food intake and body weight, prevents the 5-FU-induced decrease in food intake and body weight in the 5-FU-induced mouse model.
| M.Wt | 576.153 | |
| Formula | C28H38ClN5O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Shiomi Y, et al. Eur J Pharmacol. 2018 Jan 5;818:148-157.
2. Yoshimura M, et al. Eur J Pharmacol. 2017 Sep 15;811:30-37.
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