Chemical Structure : Z-VEID-FMK
CAS No.: 210344-96-0
Catalog No.: PC-25487Not For Human Use, Lab Use Only.
Z-VEID-FMK (Z-VE(OMe)ID(OMe)-FMK) is a specific, irreversible caspase-6 inhibitor, mimicks the effects of caspase-6 deficiency and prevents the cleavage of lamin A, significantly decreases caspase-6 activity and the oxLDL-induced DNA fragmentation and cell apoptosis.
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Z-VEID-FMK (Z-VE(OMe)ID(OMe)-FMK) is a specific, irreversible caspase-6 inhibitor, mimicks the effects of caspase-6 deficiency and prevents the cleavage of lamin A, significantly decreases caspase-6 activity and the oxLDL-induced DNA fragmentation and cell apoptosis.
M.Wt | 652.72 | |
Formula | C31H45FN4O10 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
L-Isoleucinamide, N-[(phenylmethoxy)carbonyl]-L-valyl-L-α-glutamyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-, methyl ester |
1. Gregoli PA, et al. J Cell Physiol. 1999 Feb;178(2):133-43.
2. Ruchaud S, et al. EMBO J. 2002 Apr 15;21(8):1967-77.
3. Philippe P Monnier, et al. J Neurosci. 2011 Jul 20;31(29):10494-505.
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