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Z-VRPR-fmk

Chemical Structure : Z-VRPR-fmk

CAS No.: 1381885-28-4

Z-VRPR-fmk (Z-Val-Arg-Pro-DL-Arg-FMK, z-VRPR-FMK )

Catalog No.: PC-49475Not For Human Use, Lab Use Only.

z-VRPR-fmk (Z-Val-Arg-Pro-DL-Arg-FMK) is a tetrapeptide inhibitor of mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) with Ki of 0.14 uM, shows complete inhibition at 1.25 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

z-VRPR-fmk (Z-Val-Arg-Pro-DL-Arg-FMK) is a tetrapeptide inhibitor of mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) with Ki of 0.14 uM, shows complete inhibition at 1.25 uM.

Physicochemical Properties

M.Wt 676.80
Formula C31H49FN10O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzyl ((S)-1-(((S)-1-((S)-2-(((S)-1-fluoro-6-guanidino-2-oxohexan-3-yl)carbamoyl)pyrrolidin-1-yl)-5-guanidino-1-oxopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate

References

1. Hatcher JM, et al. Bioorg Med Chem Lett. 2019 Jun 1;29(11):1336-1339.

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