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Z8539_0072

Chemical Structure : Z8539_0072

CAS No.: 2761671-37-6

Z8539_0072 (Z8539-0072 )

Catalog No.: PC-49052Not For Human Use, Lab Use Only.

Z8539_0072 is a potent SARS-CoV-2 macrodomain inhibitor that binds to the NSP3 macrodomain of SARS-CoV-2 (Mac1) with IC50 of 460 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Z8539_0072 is a potent SARS-CoV-2 macrodomain inhibitor that binds to the NSP3 macrodomain of SARS-CoV-2 (Mac1) with IC50 of 460 nM.

Physicochemical Properties

M.Wt 411.414
Formula C21H21N3O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1R)-1-(4-(3-cyclopropylureido)-2-hydroxybenzamido)-4-hydroxy-2,3-dihydro-1H-indene-2-carboxylic acid

References

1. Gahbauer S, et al. bioRxiv. 2022 Jun 28:2022.06.27.497816.

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