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Chemical Structure : ZB-16
Catalog No.: PC-20428Not For Human Use, Lab Use Only.
ZB-16 (ZB40-0016) is a potent, selective GPR119 agonist, increase intracellular cAMP with EC50 of 7.25 nM, stimulates incretin secretion.
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ZB-16 (ZB40-0016) is a potent, selective GPR119 agonist, increase intracellular cAMP with EC50 of 7.25 nM, stimulates incretin secretion.
ZB-16 has a significant antidiabetic activity connected with the increase in glucose-stimulated insulin secretion.
ZB-16 (1 mg/kg, oral) demonstrates hypoglycemic activity in rats with streptozotocin–nicotinamide-induced diabetes.
| M.Wt | 489.95 | |
| Formula | C23H21ClFN3O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Tyurenkov IN, et al. Front Endocrinol (Lausanne). 2017 Jul 7;8:152.
2. RUS Patent 2576037 C1.
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