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Chemical Structure : ZINC-3573 racemate
Catalog No.: PC-62228Not For Human Use, Lab Use Only.
ZINC-3573 racemate is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=3 uM), showing little activity against 315 other GPCRs and 97 representative kinases.
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ZINC-3573 racemate is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=3 uM), showing little activity against 315 other GPCRs and 97 representative kinases.
ZINC-3573 activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release.
| M.Wt | 307.401 | |
| Formula | C18H21N5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Lansu K, et al. Nat Chem Biol. 2017 May;13(5):529-536.
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