Chemical Structure : ZLN-005
CAS No.: 49671-76-3
Catalog No.: PC-45338Not For Human Use, Lab Use Only.
A novel small molecule PGC-1α transcriptional activator.
Packing | Price | Stock | Quantity |
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50 mg | $144 | In stock |
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A novel small molecule PGC-1α transcriptional activator; increases expression of the PGC-1α gene and downstream genes by activation of AMP-activated protein kinase, and improves glucose uptake and fatty acid oxidation without obvious cytotoxicity in L6 myotubes; produces antihyperglycemia and antihyperlipidemia effects and increases insulin sensitivity in db/db mice.
Diabetes
Preclinical
M.Wt | 250.3382 | |
Formula | C17H18N2 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 47 mg/mL |
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Chemical Name/SMILES |
1H-Benzimidazole, 2-[4-(1,1-dimethylethyl)phenyl]- |
1. Zhang LN, et al. Diabetes. 2013 Apr;62(4):1297-307.
2. Kadlec AO, et al. Hypertension. 2017 Jul;70(1):166-173.
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