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ZPCK

Chemical Structure : ZPCK

CAS No.: 26049-94-5

ZPCK (Z-L-Phe chloromethyl ketone;NSC 251810;SL 01)

Catalog No.: PC-61671Not For Human Use, Lab Use Only.

ZPCK (NSC 251810, SL 01) is a potent, pan autophagy inhibitor, inhibits the cargo degradation inside the vacuole and alters the process of autophagy in mammalian cells.

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Biological Activity

ZPCK (NSC 251810, SL 01) is a potent, pan autophagy inhibitor, inhibits the cargo degradation inside the vacuole and alters the process of autophagy in mammalian cells.
ZPCK also modulates autophagic flux in a novel model plant, Aponogeton madagascariensis.

Physicochemical Properties

M.Wt 331.796
Formula C18H18ClNO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-carbamic acid, phenylmethyl ester

References

1. Mishra P, et al. Autophagy. 2017 Aug 9:1-17.

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