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c-FMS-IN-8

Chemical Structure c-FMS-IN-8

CAS No.: 885704-21-2

c-FMS-IN-8 (1H-Pyrrole-2-carboxamide, 4-cyano-N-[4-(4-methyl-1-piperazinyl)-2-(4-methyl-1-piperidinyl)phenyl]-)

Catalog No.: PC-43376Not For Human Use, Lab Use Only.

c-FMS-IN-8 is a potent, selective c-FMS kinase inhibitor with IC50 of 0.8 nM, shows activity in collagen-induced model of arthritis in mice..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

c-FMS-IN-8 is a potent, selective c-FMS kinase inhibitor with IC50 of 0.8 nM, shows activity in collagen-induced model of arthritis in mice.

Physicochemical Properties

M.Wt 406.5239
Formula C23H30N6O
CAS No. 885704-21-2
Storage
Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 3 Month
Shipping
Solubility

DMSO

Chemical Name

1H-Pyrrole-2-carboxamide, 4-cyano-N-[4-(4-methyl-1-piperazinyl)-2-(4-methyl-1-piperidinyl)phenyl]-

Clinical Information

References

1. Illig CR, et al. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1642-8.

2. Meegalla SK, et al. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3632-7.

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