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Chemical Structure : dEF3122
Catalog No.: PC-21723Not For Human Use, Lab Use Only.
dEF3122 is a highly potent small molecule inhibitor of influenza virus replication with IC50 of 3 nM in neuraminidase activity assays, taregts NEET family of protein NAF-1.
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dEF3122 is a highly potent small molecule inhibitor of influenza virus replication with IC50 of 3 nM in neuraminidase activity assays, taregts NEET family of protein NAF-1.
Oral administration of dEF3122 for 8 wk resolved portal inflammation and fibrosis in the liver in mouse model recapitulated phenotypes of NASH associated with chronic kidney disease.
dEF3122 counteracts virus- induced mitochondria network hyperfusion.
| M.Wt | 377.46 | |
| Formula | C22H19NO3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Meyniel-Schicklin L, et al. Proc Natl Acad Sci U S A. 2024 Jan 30;121(5):e2308776121.
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